Topical caffeine protects against myopia development in monkeys

Caffeine-based eye drops created hyperopic shifts in baby rhesus monkeys during the emmetropization process, and protected against myopia development due to induced hyperopic defocus. The serum level of caffeine was similar to one cup of coffee in a human adult. This potential future myopia treatment requires further research on dosage, benefits and side effects before use in humans.

New meta-analysis on digital device use and myopia

This new systematic review and meta-analysis has evaluated use of smartphones and tablets separately to computer use and other non-screen based near work. Results are still mixed but overall there was a trend for a slightly increased risk with mobile device use alone, which increased when combined with computer use. More objective measures of screen time are needed to further explore this link.

Does myopia occur earlier in children if their parents are myopic?

This multi-ethnic study found that parental myopia was a risk factor for myopia development in pre-school age children. The age the parents became myopic themselves had a dose-dependent effect in their children if both parents had onset of myopia before age 12. Eye care practitioners can use this to identify which children may benefit from early myopia treatment intervention.

How accurate is subjective reporting of near work and outdoor time?

Young adults wearing the spectacle-mounted Clouclip device to measure viewing behaviour and light exposure also kept an activity diary. Mean daily near work and outdoor time were subjectively reported at about 150% of the objectively measured hours. This indicates the value of objective measures in research, as well as for clinical education and behaviour modification tools in future.

Light-emitting glasses alter axial length and choroidal thickness in young adults

Light-emitting glasses worn by young adults for 1-2 hours reduced axial length and increased choroidal thickness by around 20 microns compared to darkness. The study participants viewed a colour-muted television at 5m while indoors, and the changes regressed within 30 minutes. A future myopia treatment to increase ‘outdoor’ time?

Does relative peripheral refraction predict eye growth in children?

This study measured central and relative peripheral refraction (RPR) in children aged 6-7 years and 12-13 years at baseline and again one year later. There was no correlation found between central and peripheral refraction in the younger group. In the older group, more hyperopic temporal RPR was correlated with a myopic shift, but only explained 10% of the variance in refraction after 12 months.

Is there ‘physiologic’ eye growth in myopia progression?

It’s known that emmetropizing children undergo axial eye growth of around 0.1mm per year. Is this amount of growth in myopes also ‘physiologic’? In this study, data from six myopia control clinical trials was analyzed to find the axial growth component which did not result in a change in refraction. For myopes, this ‘physiologic’ growth appears to be less than 0.1mm per year, which has implications for judging progression and treatment success.

Outdoor time works to delay myopia onset – proof from Taiwan

A country-wide intervention to increase outdoor time in 5-6 year olds resulted in the prevalence of myopia decreasing from 15% in the 2014 cohort (before the intervention) to 8% in 2016 cohort (exposed to the intervention for up to two years) and was stable for three years thereafter. Increasing outdoor time works! 

Choroidal thickening in response to DIMS spectacle lens wear

This study reported that children wearing DIMS spectacle lenses showed increased sub-foveal choroidal thickness than controls at 1 week which increased in the first 6 months and was maintained at 2 years. There was a correlation between more choroidal thickening and less axial elongation, but choroidal thickening only explained around 8% of the variation in axial length.