Type: Contact lens - monthly replacement
Material: Filcon 5B (60) 75% silicone hydrogel. Class 1 UV filter.
Parameters: Customizable base curves from 7.10 to 9.80mm (0.30 steps) and diameters from 13.50 to 15.50mm (0.50 steps). Power range -0.25 to -15.00 in 0.25 steps. Spherical powers only.
Design: The Brien Holden Vision Institute’s patented Extended Depth of Focus (EDOF) technology - a single add power profile of concentric rings in varying powers.
MYLO contact lenses for myopia control are an 'Extended Depth of Focus' (EDOF) technology developed by the Brien Holden Vision Institute. The optic zone is described as "manipulating selective higher order aberrations to achieve a through focus global (both central and peripheral) retinal image quality that was optimised for points at and anterior to retina and degraded for points posterior to retina" and was "configured to offer extended depth of focus of up to +1.75D."1
One single 'add' power is available for the MYLO and these monthly contact lenses offer a variety of customizable choices for base curve, diameter and sag for each individual patient.
Myopia control mechanism
The 'extended depth of focus (EDOF)' contact lens design by the Brien Holden Vision Institute is described as having two design principles. "The first design principle aimed to reduce hyperopic defocus and induce myopic defocus across a large portion of the retina. The second design principle used extended depth of focus (EDOF) contact lenses that were designed to result in a global retinal image quality (i.e., across both the central and peripheral retina) that was improved for points on, and anterior to, the retina and degraded for points posterior to the retina to prevent axial elongation."1 This is based on optical performance and retinal image quality research undertaken by the Brien Holden Vision Institute.2,3
Myopia control efficacy
One randomized controlled trial over two years showed efficacy in slowing axial and refractive myopia progression in Chinese children aged 7-13 years. See the scientific paper summary below.
The ideal childhood myope candidate in age and refraction for the MYLO contact lens is not described by the manufacturers, but the participant characteristics in the clinical trial can be noted.
The mark’ennovy fitting guide uses refraction, keratometry and/or corneal topographical information to calculate the specific contact lens base curve, diameter and other parameters to the individual patient.
Peer reviewed science on MYLO efficacy and safety
Sankaridurg et al 2019. Myopia control with novel central and peripheral plus contact lenses and extended depth of focus contact lenses: 2 year results from a randomised clinical trial. [link to open access paper] [link to Myopia Profile paper review]
Chinese children aged 7-13 years with myopia -0.75 to -3.50D and no more than 0.75D astigmatism wore one of three test contact lens designs, or a single vision contact lens control. The test lens III achieved the greatest control of axial and refractive myopia progression: -0.81D vs -1.12D and 0.45mm vs 0.58mm compared to the single vision control over two years, representing around a 30% control effect. Children who wore their lenses 6 days a week or more had a slightly better result. Safety data was not reported, although none of the discontinuations were cited as due to adverse events.
- Sankaridurg P, Bakaraju RC, Naduvilath T, Chen X, Weng R, Tilia D, et al. Myopia control with novel central and peripheral plus contact lenses and extended depth of focus contact lenses: 2 year results from a randomised clinical trial. Ophthalmic and Physiological Optics. 2019;39(4):294-307. (link)
- Bakaraju RC, Ehrmann K, Ho A. Extended depth of focus contact lenses vs. two commercial multifocals: Part 1. Optical performance evaluation via computed through-focus retinal image quality metrics. J Optom. 2018 Jan-Mar;11(1):10-20. (link)
- Tilia D, Bakaraju RC, Chung J, Sha J, Delaney S, Munro A, Thomas V, Ehrmann K, Holden BA. Short-Term Visual Performance of Novel Extended Depth-of-Focus Contact Lenses. Optom Vis Sci. 2016 Apr;93(4):435-44. (link)